Cardiovascular

Angiogenesis and direct myocardial revascularization by Roger J. Laham, Donald S. Baim PDF

By Roger J. Laham, Donald S. Baim

ISBN-10: 1588291537

ISBN-13: 9781588291530

ISBN-10: 1592599346

ISBN-13: 9781592599349

An interdisciplinary panel of pioneers and opinion leaders assessment the elemental, preclinical, scientific, and developmental pathways to new remedy concepts, comparable to healing angiogenesis and myogenesis. The authors make the most of new organic realizing, novel healing ambitions, a number of to be had and well-studied healing recommendations, and the required imaging options to degree results. Their in-depth discussions conceal the identity of latest healing ambitions and pathways, the research of transcriptional elements, grasp change molecules, cell-based methods, chemokines, a greater realizing of the consequences of getting older, endothelial disorder, and hypercholesterolemia in accordance with angiogenic stimuli. Highlights contain exam of drug supply difficulties, results degree, stem treatment, high-risk interventions, improvement pathways, and destiny probabilities.

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Extra resources for Angiogenesis and direct myocardial revascularization

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Blood 1999;93:4196–4207. 10. Burbach KM, Poland A, Bradfield CA. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc Natl Acad Sci USA 1992;89:8185–8159. 11. Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basichelix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995;92:5510–5514. 34 Oettgen 12. Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1.

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Angiogenesis and direct myocardial revascularization by Roger J. Laham, Donald S. Baim


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