By Dr. R. Martínez, J. Vaquero, L. V. De La Morena, F. Tendillo, P. Aragonés (auth.), Professor Edward R. Hitchcock, Prof. Dr. Giovanni Broggi, Dr. Juan Burzaco, Dr. J. Martin-Rodriguez, Dr. Björn A. Meyerson, Dr. Szabolcs Tóth (eds.)
The e-book offers the main up to date details for the increasing box of stereotactic and sensible neurosurgery from eu and overseas specialists. the most recent advancements in neural transplantation and stereotactic irradiation are integrated including the stories on huge trials of analgesic surgical procedure and new ideas utilized in the therapy of numerous sensible disorders.
Read Online or Download Advances in Stereotactic and Functional Neurosurgery 9: Proceedings of the 9th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Malaga 1990 PDF
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Additional info for Advances in Stereotactic and Functional Neurosurgery 9: Proceedings of the 9th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Malaga 1990
Dopamine (DA) depletion in the striatum is the principal neurochemical deficit in PD and animal models have been designed to provide consistent host conditions for grafting experiments. In the rodent model selective unilateral striatal DA depletion and denervation has allowed reproducible pharmacological quantification of functional effects and testing of optimum donor techniques 2 . Animal models cannot reproduce the natural history, histopathology and spectrum of signs and symptomatology that occur in PD.
13. 14. ° ° 15. 16. study of autologous adrenal medullary transplantation to the corpus striatum in patients with advanced Parkinson's disease. N Engl J Med 320: 337-341 Guttma M Burns RS, Martin WRW et al (1989) PET studies of Parkinsonian patients treated with autologous adrenal implants. Can J Neurol Sci 16: 305-309 Halasz B, Pupp L, Uhlarik S et al (1963) Growth of hypophysectomized rats bearing pituitary transplant in the hypothalamus. Acta Physiol Hung 23: 287-292 Hirsh EC, Duykaerts C, Javoy-Agid F et al (1990) Does adrenal graft enhance recovery of dopaminergic neurons in Parkinson's disease?
The NA concentration in the CSF of30 normals and 23 parkinsonians was measured by the fluorophotome try, and showed the change of DA in CSF of the 17 parkinsonians who received the transplantation 1, 43 3 and 6 weeks prior and after operation. 2 nl/ml. 4ng/ml. The effect of variation of DA on clinical symptoms was more significant than NA. The lower the DA concentration was, the more serious the symptom was. The DA concentration increased in 14 and was unchanged in 3 patients. 8 ng/ml after surgery.
Advances in Stereotactic and Functional Neurosurgery 9: Proceedings of the 9th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Malaga 1990 by Dr. R. Martínez, J. Vaquero, L. V. De La Morena, F. Tendillo, P. Aragonés (auth.), Professor Edward R. Hitchcock, Prof. Dr. Giovanni Broggi, Dr. Juan Burzaco, Dr. J. Martin-Rodriguez, Dr. Björn A. Meyerson, Dr. Szabolcs Tóth (eds.)