By Pradyot Patnaik
The definitive advisor to the detrimental houses of chemical compounds
Correlating chemical constitution with toxicity to people and the surroundings, and the chemical constitution of compounds to their detrimental houses, A finished consultant to the detrimental houses of chemical compounds, 3rd Edition permits clients to evaluate the toxicity of a substance even if no experimental info exists. therefore, it bridges the distance among dangerous fabrics and chemistry. commonly up to date and increased, this reference:
- Examines organics, metals and inorganics, commercial solvents, universal gases, particulates, explosives, and radioactive components, overlaying every little thing from toxicity and carcinogenicity to flammability and explosive reactivity to dealing with and disposal practices
- Arranges harmful chemical compounds based on their chemical buildings and useful teams for simple reference
- Includes up to date info at the poisonous, flammable, and explosive houses of chemical substances
- Covers extra metals within the chapters on poisonous and reactive metals
- Updates the brink publicity limits within the office air for a few substances
- Features the newest info on business solvents and poisonous and flammable gases
- Includes various tables, formulation, and a thesaurus for speedy reference
since it offers info that allows people with a chemistry history to accomplish checks with out previous info, this finished reference appeals to chemists, chemical engineers, toxicologists, and forensic scientists, in addition to business hygienists, occupational physicians, Hazmat pros, and others in similar fields.
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Extra info for A comprehensive guide to the hazardous properties of chemical substances
Anesthetic Substance that causes dizziness, drowsiness, and headache leading to loss of consciousness and loss of response to pain. Anorexia Lack or loss of appetite for food. Anoxia Reduction of oxygen in the body tissues below physiologic levels. Anticoagulant An agent that prevents blood clotting. Antidote Substance that is administered to reverse the poisoning effects of a toxicant. Aplasia Lack of development of an organ or tissue. Arrhythmia Variation from the normal rhythm of the heartbeat.
Detoxication or biotransformation of toxicants involves two types of reactions: (1) degradation, and (2) addition or conjugation reactions. Either or both types of reactions can take place. The degradation reactions are more common and include oxidation, reduction, and hydrolysis. Such reactions result in the breakdown of the toxicants. On the other hand, the conjugation process produces adducts of the toxicants or their metabolites with endogenous metabolites. All these reactions are heavily biocatalyzed by various enzyme systems in the body.
HPLC analyses are very common for biological monitoring, as well as for several types of air and water analysis. Colorimetric, polarographic, and ion-selective electrode methods have been described for many individual compounds or types of compounds. X-ray diffraction and electron microscopy techniques may be applied for the determination of silica, asbestos, and other particulates. Metals analysis is best performed by AA. Aqueous samples are extracted using a suitable solvent. In the case of air analysis, the pollutants are adsorbed over charcoal, Tenax, or silica gel (depending on the nature of the substance) before analysis.
A comprehensive guide to the hazardous properties of chemical substances by Pradyot Patnaik